How to Give Thrombolytic Therapy Safely

Abstract

To maximize the safety of thrombolytic therapy, optimal patient selection is crucial. Absolute and relative contraindications must be sought before initiating treatment. All patients receiving thrombolysis should have serial examinations that include evaluating neurologic status as well as vital signs. To detect expanding groin hematomas, sites of recent cardiac catheterization should be monitored closely. More patients are eligible for thrombolytic therapy than is commonly realized. After a period of initial familiarization and education, the hospital staff will become confident and enthusiastic about using this important therapeutic modality.