Abstract
The enzyme γ-humulene synthase normally generates a mixture of more than 50 sesquiterpene products from a single substrate. Targeted evolution allowed the design of new mutants with greatly enhanced product specificity. The results provide a model for the divergent evolution of enzyme specificity from ancestral proteins of promiscuous function.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
