Abstract
Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) disorder characterized by recurrent or chronic abdominal pain associated with diarrhea and/or constipation.1 IBS has been redefined as a disorder of gut–brain interaction, which is classified by GI symptoms related to any combination of the following: motility disturbance, visceral hypersensitivity, altered mucosal and immune function, altered gut microbiota, and altered central nervous system processing.2 The severity of IBS is determined by the individual’s symptom experience and behaviors rather than by objective tests or histopathological markers in the bowel.
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