Abstract
BioanalysisVol. 6, No. 12 CommentaryHow the business practices of your antibody vendor could impact your ligand-binding assayMark J CameronMark J CameronSearch for more papers by this authorPublished Online:31 Jul 2014https://doi.org/10.4155/bio.14.87AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: antibodyantibody marketingcommercial sourced antibodyhistorical clone numberslicensingligand-binding assayOEMoriginal equipmentrelabeling practices manufacturerReferences1 Bordeaux J, Welsh A, Agarwal S et al. Antibody validation. Biotechniques 48(3), 197–209 (2010).Link, CAS, Google Scholar2 Rup B, O'Hara D. Critical ligand binding reagent preparation/selection: when specificity depends on reagents. AAPS J. 9(2), E148–E155 (2007).Crossref, Medline, CAS, Google Scholar3 O'Hara DM, Theobald V, Egan AC et al. Ligand binding assays in the 21st century laboratory: recommendations for characterization and supply of critical reagents. AAPS J. 14(2), 316–328 (2012).Crossref, Medline, Google Scholar4 Marx V. Finding the right antibody for the job. Nat. Methods 10(8), 703–707 (2013).Crossref, Medline, CAS, Google Scholar5 Staack RF, Stracke JO, Stubenrauch K, Vogel R, Schleypen J, Papadimitriou A. Quality requirements for critical assay reagents used in bioanalysis of therapeutic proteins: what bioanalysts should know about their reagents. Bioanalysis 3(5), 523–534 (2011).Link, CAS, Google Scholar6 Geist BJ, Egan AC, Yang TY, Dong Y, Shankar G. Characterization of critical reagents in ligand-binding assays: enabling robust bioanalytical methods and lifecycle management. Bioanalysis 5(2), 227–244 (2013).Link, CAS, Google Scholar7 Couchman JR. Commercial antibodies: the good, bad and really ugly. J. Histochem. Cytochem. 57(1), 7–8 (2009).Crossref, Medline, CAS, Google Scholar8 Saper CB. An open letter to our readers on the use of antibodies. J. Comp. Neurol. 493(4), 477–478 (2009).Crossref, Google ScholarFiguresReferencesRelatedDetails Vol. 6, No. 12 Follow us on social media for the latest updates Metrics Downloaded 128 times History Published online 31 July 2014 Published in print June 2014 Information© Future Science LtdKeywordsantibodyantibody marketingcommercial sourced antibodyhistorical clone numberslicensingligand-binding assayOEMoriginal equipmentrelabeling practices manufacturerFinancial & competing interests disclosureThe author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download
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