Abstract
This chapter will focus on cell signaling and signal transduction, that is, the extremely complex series of reactions by which cells receive and react to external signals (for reviews, see Hunter 2000; Pawson and Nash 2000). Particularly, it will deal with those processes that are regulated by protein phosphorylation. The topic is of significance considering that approximately 15 to 20% of the entire human genome (at least 6400 genes) is devoted to the expression of the molecules implicated.
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