Abstract
How Normal Cells Can Win the Battle for Survival Against Cancer Cells
Highlights
During the early stages of tumorigenesis, cancerous cells undergo rapid and uncontrolled cell division as they invade the surrounding tissue
A recent study showed that cancerous cells in fruit flies manage this feat by inducing neighboring cells to spontaneously destroy themselves and filling the vacated space left behind in a process known as cell competition
In this issue of PLoS Biology, Yoichiro Tamori et al provide evidence that this battle occurs in mammalian tissues and uncover what determines the winners and losers when cells compete
Summary
During the early stages of tumorigenesis, cancerous cells undergo rapid and uncontrolled cell division as they invade the surrounding tissue. How Normal Cells Can Win the Battle for Survival Against Cancer Cells In this issue of PLoS Biology, Yoichiro Tamori et al provide evidence that this battle occurs in mammalian tissues and uncover what determines the winners and losers when cells compete.
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