Abstract
It is the responsibility of a major medical journal to publish information that will constructively influence patient care. Optimally, each manuscript should transmit a ‘take-home message’. And this one does. So, let us track the evolution of the message presented in the review by Som et al. [1] in this issue of the World Journal of Surgery. When the Framingham Heart Study began in 1948, hypertension and a rising plasma cholesterol were considered to be routine and inevitable consequences of aging. However, physicians rapidly recognized that blood pressure control was good. But, manipulation of plasma cholesterol is conceptually trickier.
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