Abstract
EVIDENCE-BASED ANSWER Pseudoephedrine is associated with an increase of less than 2 mmHg in systolic blood pressure systolic blood pressure (SBP) and no effect on diastolic blood pressure (DBP) in patients with hypertension. Phenylephrine, in patients with or without hypertension, has no effect on blood pressure at the usual 10-mg dose (SOR: C, metaanalyses of RCTs with disease-oriented evidence).
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