How is NLR and PLR affected in Type 2 diabetes mellitus compared to healthy population?

Abstract

Objective: Diabetes Mellitus (DM); has become an important public health problem in Turkey and in the world. In this study, we aimed to investigate the effect of neutrophil / lymphocyte ratio and platelet / lymphocyte ratio in diabetic patients compared to healthy population in terms of cost effectiveness.
 Material and Methods: A control group consisting of 82 diabetics and 85 healthy individuals who applied to the internal medicine outpatient clinic between January 2019 and November 2019 were included in the study. The patients were divided into two groups as those with diabetes and healthy individuals. Files were scanned retrospectively and hemoglobin, mean platelet volume (MPV), glycosylated hemoglobin (HbA1c), hematocrit counts (hct), neutrophil and lymphocyte counts, and neutrophil-lymphocyte ratio (NLR), platelet count (plt), platelet lymphocyte ratio (NLR) PLR) has been recorded.
 Results: We retrospectively compared the demographic and laboratory parameters of the healthy group and the diabetic patients (82 patients and 85 healthy). The mean age of the diabetic group was 55.9 years, while the mean age of the healthy group was 37.5. Mean NLR was 2.4 and 2.1 in diabetic and healthy groups, respectively. NLR value was higher in diabetic group compared to healthy group and there was no statistically significant difference (p = 0.07). MPV values in diabetic group and healthy group were 8.53 and 8.51, respectively, and there was no significant relationship between them (p = 0.81). PLR value was 145.9 and 146.7 in diabetic group and healthy group, respectively, and we did not find any significant relationship (p = 0.97).
 Discussion: As a result; In our study, when we evaluated the diabetic group within the diabetic group and the healthy group, we could not find a statistically significant relationship between the groups in terms of hematological parameters.