Abstract
In India, head and neck cancer including all sites is the most common cancer in terms of incidence and mortality among both sexes combined as per GLOBOCAN 2018, with lip and oral cavity being the most common site.[1] Squamous cell cancer of head neck (HNSCC) constitutes the majority of all head and neck malignancies.[2] Most of the patients present in the advanced stage.[3] Even localized HNSCC are notorious for high rates of recurrence in spite of curative modalities of treatment.[4] Treatment for advanced recurrent HNSCC is palliative systemic therapy provided that patients have a good Eastern Cooperative Oncology Group (ECOG) performance score (PS) with normal organ function.
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