Abstract

BackgroundYouth experiencing homelessness are at high risk for suicide, yet few studies have evaluated risk reduction interventions targeting suicidal ideation in this vulnerable population. A comprehensive approach to risk-reduction is needed that addresses basic needs and provides targeted interventions for those at highest risk. The protocol described builds on the design of the first randomized trial of Housing First (HF) for homeless youth. The primary objective is to determine whether housing combined with supportive services that include suicide screening and targeted psychotherapy (Cognitive Therapy for Suicide Prevention) is effective for reducing suicidal ideation and other secondary outcomes (depression and suicide attempts). Additionally, we will explore mediators of the treatment effect (housing stability and substance use) and determinants of implementation.MethodsYouth recruited to the HF trial will be randomized to HF + supportive services (n = 120), or supportive services alone (n = 120). The “Suicide Treatment Education and Prevention” (STEP) protocol will additionally screen youth in both arms at baseline and 3 months for suicidal ideation (SSI-W). Those who screen as moderate risk for suicide (SSI-W ≥ 10) will be offered CTSP, which includes up to 9 sessions over the first 6 months following enrollment. CTSP will be delivered in one-on-one sessions by a trained advocate. Research assessments will be collected to assess outcomes (including suicidal ideation) at baseline, 3, 6, 9 and 12 months. Qualitative interviews with subjects receiving CTSP and other stakeholders will explore implementation determinants.DiscussionThe study will fill an important gap in the literature about the added benefit of HF combined with supportive services including suicide screening and treatment for reducing suicidal ideation in homeless youth. With the urgent need to address both homelessness and suicide risk, evidence is needed about services that can be integrated into delivery settings for youth experiencing homelessness.Trial registrationNCT04135703. Date of registration: October 23, 2019.

Highlights

  • Youth experiencing homelessness are at high risk for suicide, yet few studies have evaluated risk reduction interventions targeting suicidal ideation in this vulnerable population

  • In the present protocol description, we describe the design of the secondary study, including how the suicide prevention services will be delivered and how the study will answer important questions regarding the added benefit of housing first (HF) for addressing suicide risk in a highrisk population of youth

  • Among chronically homeless adults with severe mental illness, suicidal ideation was not significantly reduced when compared to a community services control group [28]. These results suggest targeted suicide prevention may be needed for individuals with severe suicidal ideation who are at highest risk for suicide

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Summary

Introduction

Youth experiencing homelessness are at high risk for suicide, yet few studies have evaluated risk reduction interventions targeting suicidal ideation in this vulnerable population. A term often used to describe homeless adolescents and young adults under age 25 [8], are a vulnerable population who often experience trauma both before and after becoming homeless [9,10,11], as well as significant mental health and substance use comorbidity. The lived experiences of homeless youth combined with a high prevalence of substance use disorders put them at increased risk for suicidal ideation and attempts [12,13,14]. Studies estimate approximately 40% of homeless youth have attempted suicide at least once in their lifetime [11, 12], much higher than the 1.9% of young adults in the U.S general population who reported suicide attempts in a 2018 household-based survey [15]

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