Hot-injection Polyol 공정에 의해 제조된 Fe3O4나노입자의 Hyperthermia 특성

Abstract

<TEX>$Fe_3O_4$</TEX> 나노입자는 hot-injection 제조법에 의해 제조되었으며 반응물질의 injection time에 변화를 주었다. 격자구조는 x-ray diffraction(XRD) 측정을 통해 Fd-3m 공간군을 갖는 cubic inverse spinel 구조로 분석되었으며, <TEX>$Fe_3O_4$</TEX> 나노입자의 형상은 high-resolution transmission electron microscope(HR-TEM)으로 분석하였다. 반응물질을 각각 0.5분, 60분인 젝션시 각각 7.63 nm, 21.73 nm의 <TEX>$Fe_3O_4$</TEX> 나노입자 사이즈를 얻을 수 있었다. <TEX>$Fe_3O_4$</TEX> 나노입자의 자기적 특성은 다양한 온도에서 vibrating sample magnetometer(VSM)과 M<TEX>$\ddot{o}$</TEX>ssbauer spectroscopy로 측정하였으며, hyperthermia 측정을 통해 반응물질의 injection time이 60분일 때 50 kHz의 250 Oe에서 <TEX>$Fe_3O_4$</TEX> 나노입자 파우더의 온도가 약 <TEX>$120^{\circ}C$</TEX>임을 관측할 수 있었다. The <TEX>$Fe_3O_4$</TEX> nanoparticle was synthesized by the hot-injection method while varying the injection time of the precursor solution. The crystal structure was determined to be cubic inverse spinel with space group of Fd-3m based on X-ray diffraction (XRD) measurements and the morphology of the prepared <TEX>$Fe_3O_4$</TEX> nanoparticle was studied with a high-resolution transmission electron microscope (HR-TEM). When the precursor solution was injected for 0.5 min, the size of the <TEX>$Fe_3O_4$</TEX> nanoparticle was 7.63 nm, while the size of the obtained particle was 21.27 nm with the injection time of 60 min. The magnetic properties of the prepared <TEX>$Fe_3O_4$</TEX> nanoparticle were investigated by both vibrating sample magnetometer (VSM) and <TEX>$^{57}Co$</TEX> M<TEX>$\ddot{o}$</TEX>ssbauer spectroscopy at various temperatures. From the hyperthermia measurement, we observed that the temperature of the <TEX>$Fe_3O_4$</TEX> nanoparticle powder reached around <TEX>$120^{\circ}C$</TEX> under 250 Oe at 50 kHz, when the injection time of the precursor solution was 60 min.