Abstract
How commensals influence intestinal immunity is incompletely understood. In this issue of Immunity, Eshleman etal. demonstrate that microbiota-derived butyrate restrains tuft cell development via HDAC3 modulation in intestinal epithelial cells, showing how microbial metabolites impact intestinal type 2 immunity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have