Abstract
Quantitative differences in lytic activity of a given phage against various susceptible host bacteria are common among lactic streptococcal bacteriophages. Changes in activity pattern against a range of hosts were quickly established by propagating a given phage on a particular host. Activity patterns determined by the parent host were highly reproducible, did not change with repeated propagations on the same host, and reflected virulence of a homogeneous progeny from replication of a single phage particle. A second kind of host-induced change was calcium requirements of phages for rapid proliferation. Three out of eight phage strains were altered in calcium requirements by a single propagation on a different host.
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