Host factors in carcinoma of the uterine cervix

Abstract

Host factors, particularly endocrine, were investigated in 173 autopsied patients with cancer of the cervix, compared to 203 noncancerous women. More women of short stature were present in the cancer group. No significant increase of genital endocrine abnormalities accompanied cervical cancer. The endocrine and urinary tract alterations that occurred most commonly were considered as likely accompaniments or secondary complications of cancer growth. The observations are interpreted to indicate that cancer of the cervix more characteristically arises through local cervical processes than through generalized body abnormalities.