Host and environmental predictors of exhaled breath temperature in the elderly

Esmée Bijnens,Maurice P Zeegers,Nicky Pieters,Luc Int Panis,Nelly Saenen,Bianca Cox,Tim S Nawrot,Bram Janssen,Harrie Dewitte,Evi Dons

doi:10.1289/isee.2013.o-3-34-04

Abstract

Background Exhaled breath temperature has been suggested as a new method to detect and monitor pathological processes in the respiratory system. The putative mechanism of this approach is based upo...

Highlights

Exhaled breath temperature has been suggested as a new method to detect and monitor pathological processes in the respiratory system
Exhaled breath temperature has been proposed to reflect airway inflammation as a positive relationship was observed between exhaled breath temperature and bronchial blood flow and exhaled nitric oxide in asthmatic patients [1]
In other studies of asthmatic subjects, exhaled breath temperature was found to correlate with both exhaled nitric oxide (eNO) and sputum eosinophils [2] while treatment with inhaled corticosteroids led to a decline in the temperature of the exhaled breath and eosinophils and improved expiratory

Summary

Introduction

Exhaled breath temperature has been suggested as a new method to detect and monitor pathological processes in the respiratory system. Exhaled breath temperature has been proposed to reflect airway inflammation as a positive relationship was observed between exhaled breath temperature and bronchial blood flow and exhaled nitric oxide (eNO) in asthmatic patients [1]. In other studies of asthmatic subjects, exhaled breath temperature was found to correlate with both eNO and sputum eosinophils [2] while treatment with inhaled corticosteroids led to a decline in the temperature of the exhaled breath and eosinophils and improved expiratory population at large are necessary in order to identify the factors that influence exhaled breath temperature. We measured exhaled breath temperature among 151 persons aged 60 to 80, to study the influence of host factors including gender and age as well as environmental factors such as physical activity, blood pressure, cholesterol levels and residential proximity to major roads as a proxy for exposure to traffic-related air pollution including ultra fine particulates [5,6,7]

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Conclusion