Abstract

Acute animal toxicity data are useful in comparing a series of compounds with regard to a given toxic endpoint. Such information is not obtainable from human populations, and clinicians must often be guided by empiric judgement in treating acute ingestions. This experimental survey compared the calculated percent of cases hospitalized for 12 common substances ingested by young children as reported by the National Clearinghouse for Poison Control Centers for 1975-1976. Such ratios are offered as measures of clinical toxicity and as helpful modes of input in guiding patient management.

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