Hospital-based surveillance of enteric parasites in Kolkata

Avik Mukherjee,Mihir Bhattacharya,Mrinmoy Ghosh,Punam Chowdhury,Krishnan Rajendran,Sandipan Ganguly

doi:10.1186/1756-0500-2-110

Avik Mukherjee, Mihir Bhattacharya + Show 4 more

Open Access

https://doi.org/10.1186/1756-0500-2-110

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Abstract

BackgroundDiarrhoea is the second leading cause of illness and death in developing countries and the second commonest cause of death due to infectious diseases among children under five in such countries. Parasites, as well as bacterial and viral pathogens, are important causes of diarrhoea. However, parasitic infections are sometimes overlooked, leading after a period of time to an uncertain aetiology. In this paper we report the prevalence of Giardia lamblia, Entamoeba histolytica and Cryptosporidium sp. in and around Kolkata.FindingsA hospital-based laboratory surveillance study was conducted among the patients admitted between November 2007 and October 2008 to the Infectious Diseases (ID) Hospital (Population = 1103) with diarrhoeal complaints. Of the 1103 samples collected, 147 were positive for Giardia lamblia, 84 for Cryptosporidium sp. and 51 for Entamoeba histolytica. For all these parasites there was a high rate of mixed infection with common enteric viruses and bacteria such as Rotavirus, Vibrio cholerae and Shigella sp. There were also cases of co-infection with all other diarrheogenic pathogens. The age group ≥ 5 years had the highest prevalence of parasites whereas the age group >5 – 10 years was predominantly infected with Giardia lamblia (p =< 0.001; Odds ratio (OR) = 3.937; 95% Confidence interval (CI) = 1.862 – 8.326) and with all parasites (p = 0.040; OR = 2.043; 95% CI = 1.033 – 4.039). The age group >10 – 20 years could also be considered at risk for G. lamblia (p = 0.009; OR = 2.231; 95% CI = 1.223 – 4.067). Month-wise occurrence data showed an endemic presence of G. lamblia whereas Cryptosporidium sp. and E. histolytica occurred sporadically. The GIS study revealed that parasites were more prevalent in areas such as Tangra, Tiljala and Rajarhat, which are mainly slum areas. Because most of the population surveyed was in the lower income group, consumption of contaminated water and food could be the major underlying cause of parasitic infestations.ConclusionThis study provides important information on the occurrence and distribution of three important intestinal parasites and indicates their diarrheogenic capacity in Kolkata and surrounding areas.

Highlights

Diarrhoea is the second leading cause of illness and death in developing countries and the second commonest cause of death due to infectious diseases among children under five in such countries
Giardia lamblia was the sole infection in 31.2% of cases and there was mixed infection with other common pathogens in the
The spatial distribution indicated that Dum Dum and Tiljala had the highest incidences of Enatmoeba infection followed by Narkeldanga and Phoolbagan (Fig. 2)

Summary

Introduction

Diarrhoea is the second leading cause of illness and death in developing countries and the second commonest cause of death due to infectious diseases among children under five in such countries. A global estimate suggests that 19% of total child deaths are attributable to diarrhoea and 73% of these deaths are concentrated in 15 developing countries [1]. It is the second commonest cause of death due to infectious diseases in children under five and a major cause of adult death in such countries [2]. In this paper we describe the occurrence of three most abundant enteric parasites, Giardia lamblia, Entamoeba histolytica and Cryptosporidium parvum, in Kolkata and surrounding areas

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