Abstract
Objective: to analyze the clinical course of ventilator-associated pneumonia caused by Stenotrophomonas maltophilia in infants as a high-risk group for the development of hospital acquired infection, as well as a study of the sensitivity of the pathogen to antibiotics. Eighteen infants (14 premature and 4 mature infants) with ventilator -associated pneumonia due to (Stenotrophomonas maltophilia) were monitored. The disease occurred in the majority (72%) of infants as a monoinfection, more often in severe and acute form with severe toxicosis, trophic disorders, severe respiratory failure, bilateral lung and bronchial lesions. In 33% of children, mostly premature, there was a change in the pathogen, which increased the severity and duration of the disease. Pneumonia had complications in the form of sepsis (6%) and bronchopulmonary dysplasia (28%). Most Stenotrophomonas maltophilia retained sensitivity to ticarcillin + clavulanate, ciprofloxacin, chloramphenicol and co-trimoxazol.
Highlights
ОСП «Научно-исследовательский клинический институт педиатрии им. акад
Hospital-acquired pneumonia associated with the causative agent Stenotrophomonas maltophilia, in newborn infants
Objective: to analyze the clinical course of ventilator-associated pneumonia caused by Stenotrophomonas maltophilia in infants as a high-risk group for the development of hospital acquired infection, as well as a study of the sensitivity of the pathogen to antibiotics
Summary
Госпитальная пневмония, ассоциированная с возбудителем Stenotrophomonas maltophilia, у новорожденных детей. Hospital-acquired pneumonia associated with the causative agent Stenotrophomonas maltophilia, in newborn infants. Для цитирования: Кушнарева М.В., Мархулия Х.М., Дементьева Г.М., Чурсина Е.С., Е.С.Кешишян, Семенов А.В. Objective: to analyze the clinical course of ventilator-associated pneumonia caused by Stenotrophomonas maltophilia in infants as a high-risk group for the development of hospital acquired infection, as well as a study of the sensitivity of the pathogen to antibiotics. For citation: Kushnareva M.V., Marhulia H.M., Dementyeva G.M., Chursina E.S., Keshishian E.S., Semenov A.V. Hospital-acquired pneumonia associated with the causative agent Stenotrophomonas maltophilia, in newborn infants. Хотя проблеме ИВЛ-ассоциированной пневмонии у недоношенных новорожденных детей посвящено много научных исследований [1,2,3,4,5,6], однако особенности клинического течения заболевания, в том числе с учетом этиологического фактора, изучены мало [7,8,9]. Цель: исследовать особенности клинического течения ИВЛ-ассоциированной пневмонии, обусловленной Sten. maltophilia, у недоношенных новорожденных детей и чувствительность возбудителей заболевания к антибиотикам
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