Abstract

Guggenbichler S1, M Hell2 and Guggenbichler JP3* Author Affiliations 1Division of vascular surgery and endovascular surgery of the University of Salzburg, Austria 2MEDILAB OG- Department of Clinical Microbiology and Hygiene - Teaching Laboratory of the Paracelsus Medical University, Salzburg, Austria 3AmiStec. Laboratory, Kössen, Austria Received: July 01, 2020 | Published: September 18, 2020 Corresponding author: Guggenbichler JP, Department or Pediatrics, AmiSTec GMbH und Co KG, Kössen, Austria DOI: 10.26717/BJSTR.2020.30.004967

Highlights

  • World wide, millions of patients are affected annually by healthcare-associated infections (HCAI), impacting up to 8 000 patients in European Hospitals on any given day [1]

  • Bacteria and other microbes evolve in response to their environment and inevitably develop mechanisms to resist being killed by antibiotics and disinfectants [6]

  • The evolution of antibiotic resistance is occurring at an alarming rate and is outpacing the development of new countermeasures

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Summary

Introduction

Millions of patients are affected annually by healthcare-associated infections (HCAI), impacting up to 8 000 patients in European Hospitals on any given day [1]. There are reports of the emergence of alcohol tolerant/insensitive microorganisms e.g. vancomycin resistant enterococci after extensive hand disinfection. This phenomenon has the potential to undermine the effectiveness of alcohol-based disinfectant standard precautions [16,17,18]. Considering the above information it was mandatory to reassess preventive measures for hospital acquired infections and to curb the dramatic increasing rate of emerging resistant microorganisms. The development of selfsanitizing surfaces with a broad spectrum of activity, long lasting to permanent antimicrobial activity without induction of resistance seems to be a promising solution for this problem if the requirements for the prevention of hospital acquired infections are met.

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