Abstract

Central Role of the Liver in Metabolism.- Regulation of Intermediary Metabolism by Substrate Supply, Hormone Concentrations and Nervous Activity.- Hormonal Adaptations to Energy Intake and Determinants of Energy Expenditure.- Hormonal Adaptation to Over- and Underfeeding.- Hormonal and Metabolic Determinants of Energy Expenditure in Humans.- Sympathetic Nervous System in the Regulation of Thermogenesis.- Organ Contribution to Energy Expenditure in Humans.- Thermogenic Role of Brown Adipose Tissue and Skeletal Muscle in Humans.- Physiological Significance of Substrate Cycling in Humans.- The Role of Triglyceride-Fatty Acid Cycling and Glucose Cycling in Thermogenesis and Amplification of Net Substrate Flux in Human Subjects.- Hormones, Nutrition, Obesity, Cachexia.- Hormonal and Nutritional Factors Contributory to Obesity.- Thermogenesis in Obesity and Cachexia.- Hormonal and Nutritional Factors Contributing to Tumour Cachexia.- Catabolism in Patients with Liver Cirrhosis.- Muscle Protein Turnover.- Physiological and Pathophysiological Regulation of Human Muscle Protein Turnover.- Nutritional Support Following Trauma and the Use of Indirect Calorimetry.- Influence of Stress on the Endocrine System and Nutritional Support in Surgical Patients.- Importance of Indirect Calorimetry for the Nutrition of Intensive Care Patients.- Overview.

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