Hormone therapy and exercise as interventions for post-menopausal women with greater trochanteric pain syndrome. A randomised clinical trial

Abstract

Background: Greater trochanteric pain syndrome (GTPS) is a debilitating condition, prevalent in post-menopausal women. A positive association between high oestrogen levels and tendon health may exist. Menopausal hormone therapy (MHT) could reduce the incidence of tendon abnormality in post-menopausal women, particularly when combined with exercise. This blinded 2 x 2 factorial randomised clinical trial (GLoBE Hip Trial) aimed to determine the effect of MHT and exercise on tendon pain and function in post-menopausal women with GTPS.