Abstract
The climacteric is a physiological period of the female reproductive cycle characterized by a decrease in the levels of sex hormones, mainly estrogen. It consists of several phases, with amenorrhea as the initial clinical manifestation followed by long-term changes, such as vaginal atrophy. In this context, hormone replacement therapy (HRT) aims to improve the symptoms of female reproductive senescence, seeking to provide a comfortable physical and psychological condition during this period. However, as with any drug treatment, HRT has its risks and benefits, and it is up to the medical practitioner, in agreement with the patient, looking for the best therapeutic option, minimizing the risks and consequences resulting from this clinical approach.
Highlights
The climacteric, due to the sensitive hormonal drop, mainly estrogenic, may cause uncomfortable symptoms that decrease the quality of life of several women [1]
Vaginal atrophy, which typically occurs in the climacteric, is characterized by Integr J Med Sci.2020;7:3p a thinner epithelial layer and less local blood flow
[5] Women in this period have greater bone fragility compared to young women and, a higher risk of fractures [6]
Summary
Laura Gomes Lima a, Najwa Munir Tayfour a, Paula Cristina Oliveira Lemos a, Maryanna Freitas Alves a, Isadora Mota Ferreira a, Eriston Vieira Gomes b c a University of Rio Verde, UniRV, Medical School, Rio Verde, GO, Brazil b Ribeirão Preto Medical School, FMRP, University of São Paulo, USP, Ribeirão Preto, SP, Brazil c Morgana Potrich College, FAMP, Medical School, Mineiros, GO, Brazil
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