Abstract
The levels of met-enkephalin in the rat neurohypophysis were measured by radioimmunoassay in four groups of animals. The groups were a control untreated group, a sham operated group, a group subjected to 1% body weight haemorrhage which is an acute hormone releasing stimulus, and a group subjected to four days 2% saline imbibition which is a chronic hormone releasing stimulus. In none of the groups was the met-enkephalin level significantly different from the control value of 1.90±0.18 ng/gland (n=10), suggesting that there was no deplation of met-enkephalin concomitant with the depletion of neurohypophysial hormones in the rat.
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