Hormone drugs and surgery treatment for Takayasu arteritis

Abstract

Objective To summarize surgical treatment of Takayasu arteritis, and analysis the drug treatment effect during the perioperative period. Methods Retrospective analysis 46 patients with Takayasu's arteritis disease and received cardiovascular surgery between January 2010 to December 2015, in Anzhen Hospital. By collecting their clinical characteristics, preoperative drug therapy, surgical treatment, pathological examination results to analyze operation conditions, effect of drugs and preoperative conditions. Results The perioperative mortality rate was 2.2% and the complication rate was 23.9% in 46 patients. There were 34 patients with symptomatic relief in the perioperative period, 11 patients didn`t take hormone drugs before operation. There were 11 cases of complications during the perioperative period, of which 7 patients were in active stage and 10 patients had not been used before operation. Conclusion The surgical treatment of patients with Takayasu's arteritis disease can effectively improve symptoms. The patients in Takayasu's arteritis active stage will affect the outcome of the surgery. Rational use of hormone drugs before surgery, can effectively control the patient's condition, improve the rate of remission of symptoms, and effectively reduce the incidence of perioperative complications. Key words: Takayasu's arteritis; Cardiac Surgery; Hormone drugs treatment; Perioperative complications