Abstract
Estrogens and progesterone regulate the differentiation and function of chick oviduct (1–4). Our attention has been focused on hormonal regulation of ovalbumin synthesis, since this single polypeptide comprises 50–60% of the protein synthesized in the fully differentiated oviduct. This feature allows potentially for isolation of the molecular elements involved in specific protein synthesis, including specific polysomes, mRNA, and genes, and an analysis of various regulatory steps between transcription and translation of specific mRNAs, as affected by developmental and hormonal variables.
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