Abstract
Objective: Ovarian high-grade serous carcinoma (HGSC) is genetically unstable and rapidly growing and diagnosed at advanced stages. Immunohistochemical profiles have demonstrated differential expression of estrogen receptor alpha (ER) and progesterone receptor (PR) in HGSC. Our objective was to investigate the ER and PR in HGSC and its precursor lesions and to assess the influence of ER/PR subtype on OS and ER/PR-driven pathogenesis in HGSC.
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