Abstract
SummaryThe fatty acid compostions of the sterol ester and phospholipid fractions of mammary carcinomas and a derived, transplantable sarcoma were determined; the composition of the sarcoma differed from that of the carcinoma. Hormonal modification (ovariectomy plus 50 μg estradiol-17β with or without progesterone) of hosts bearing mammary carcinomas did not per se result in changes in the fatty acid composition of the phospholipid fraction of the carcinomas, except in those carcinomas which became laden with fat. The phospholipid and sterol ester fractions of fat-laden carcinomas had increased proportions of the shorter chain (C10-14) fatty acids and decreased proportions of polyunsaturated fatty acids but differences were not as great as in the triglycerides.
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