Abstract

Sexual receptivity was induced by sequential injections of estrogen and progesterone in ovariectomized female rats which had bilateral, monopolar electrodes permanently implanted into either the medial preoptic area (MPOA) or the medial basal hypothalamus (MBH). Intermittent electrical stimulation of the MPOA during the first 6 hours of estrogen priming significantly reduced the intensity of estrous behavior measured 2 days later. Comparable stimulation of the MBH produced a non-significant increase in receptivity. The use of electrical stimulation to study the ways in which hormones affect central sites of action is discussed.

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