Abstract
The sudden drop in the level of postpartum certain hormones, especially estrogens and progesterone, promotes mood disorders. Some women may have severe symptoms of postpartum depression, that need timely diagnosis and proper treatment. Women with premenstrual syndrome symptoms are particularly at risk of depression.
 To prevent the dangerous consequences of unrecognized postpartum depression, a requirement was introduced in 2019 in Poland for gynecologists to interview pregnant women and to exclude the occurrence of depression in the postpartum period.
 The aim of the study is to present the hormonal determinants of postpartum depression with particular attention to risk factors.
Highlights
Postpartum depression – definition and epidemiologyPeripartum depression is defined as an episode of major depressive disorder (MDD) occurring during pregnancy and within 4 weeks of delivery [1]
According to the World Health Organization (WHO), the perinatal period is defined as the period of pregnancy and 6 weeks after delivery
Due to the low level of estrogen in the blood, there is a change in the secretion of gonadotropin-releasing hormone (GnRH) by the hypothalamus wherein the frequency and the amplitude of its secretion increases, which causes a gradual increase in the secretion of follicle-stimulating hormone (FSH) by the pituitary gland
Summary
The sudden drop in the level of postpartum certain hormones, especially estrogens and progesterone, promotes mood disorders. Some women may have severe symptoms of postpartum depression, that need timely diagnosis and proper treatment. Women with premenstrual syndrome symptoms are at risk of depression. The aim of the study is to present the hormonal determinants of postpartum depression with particular attention to risk factors. Nagły spadek stężenia niektórych hormonów po porodzie, zwłaszcza estrogenów i progesteronu, sprzyja zaburzeniom nastroju. Niektóre kobiety mogą mieć poważne objawy depresji poporodowej, które wymagają szybkiej diagnozy i odpowiedniego leczenia. Aby zapobiec niebezpiecznym konsekwencjom nierozpoznanej depresji poporodowej, w 2019 roku wprowadzono w Polsce wymóg przeprowadzania testów u kobiet w ciąży i po porodzie, aby wykluczyć występowanie u nich depresji. Celem pracy jest przedstawienie hormonalnych uwarunkowań depresji poporodowej ze szczególnym zwróceniem uwagi na czynniki ryzyka
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