Abstract
The study of 54 subjects infected with Necator americanus showed a high correlation between faecal blood loss measured with 51Cr and hookworm infection estimated either by the number of parasites recovered or by oviposition. Faecal bloos loss was of the order of 0·03 ml. per worm daily, and 2·1 ml. per 1,000 eggs per gramme of faeces. The number of eggs per female Necator was about 3,000 per day and 30 per gramme of faeces. In 5 cases studied at different levels of haemoglobin concentration the faecal blood loss and oviposition did not show any consistent pattern. The red cell survival measured with 51Cr was corrected after iron treatment in 4 out of 5, although they were carrying heavy infections, indicating that the toxin of the parasites does not interfere with the life span of the erythrocytes.
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