Homoselective synthesis of 5‐substituted 1H‐tetrazoles and one‐pot synthesis of 2,4,5‐trisubstuted imidazole compounds using BNPs@SiO2‐TPPTSA as a stable and new reusable nanocatalyst

Abstract

Considering the importance of tetrazole and imidazole derivatives in pharmacy, industry, and explosives, BNPs@SiO2‐TPPTSA was easily prepared and used as an effective, stable, and renewable nanocatalyst for the homoselective synthesis of different 5‐substituted 1H‐tetrazoles and atom economic synthesis of 2,4,5‐trisubstituted‐1H‐imidazoles in solventless conditions. BNPs@SiO2‐TPPTSA was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X‐ray diffraction (XRD), energy dispersive X‐ray analysis (EDX), thermal gravimetric‐differential thermal analysis (TGA‐DTA), mapping, pH analysis, and Fourier transform infrared (FT‐IR) techniques. Furthermore, the catalyst recycled for at least sequential five loads without a remarkable drop‐in catalytic activity.