Homopiperazine (Hexahydro-1,4-diazepine)

R Alan Aitken,Dheirya K Sonecha,Alexandra M Z Slawin

doi:10.3390/m1200

Abstract

The X-ray structure of the title compound has been determined for the first time. Data on its 1H–13C-NMR coupling constants and 15N-NMR spectrum are also given.

Highlights

The fundamental heterocyclic compound hexahydro-1,4-diazepine or “homopiperazine” 1 was first reported in 1899 [1,2] and a convenient industrial preparation was described in 1961 [3]. It is commercially available from several major suppliers and it has recently found various applications, including as a component of liquids for CO2 capture [4] and as a component of various organic and organic/inorganic supramolecular ionic salts and transition metal complexes
The materials are often characterised by X-ray diffraction and so there are a large number of X-ray structures involving a homopiperazinium dication in salts or mixed salts with, for example, carboxylic acids [5,6,7], potassium perchlorate [8], ammonium perchlorate [9], manganese sulfate oxalate [10], cobalt sulfate [11], zinc phosphate [12], arsenic oxide [13], tellurium phosphate [14], cadmium phosphate [15], cadmium chlorides [16,17], lead bromide [18], bismuth iodide [19], uranium fluoride [20] and uranium sulfate [21]
There are a significant number of structures in which homopiperazine acts as a bidentate ligand on nickel [22,23], copper [24] and platinum [25,26,27,28]

Summary

Introduction

The fundamental heterocyclic compound hexahydro-1,4-diazepine or “homopiperazine” 1 was first reported in 1899 [1,2] and a convenient industrial preparation was described in 1961 [3] At present, it is commercially available from several major suppliers and it has recently found various applications, including as a component of liquids for CO2 capture [4] and as a component of various organic and organic/inorganic supramolecular ionic salts and transition metal complexes.

Results

H and 13 Coperator

Experimental