Abstract
Eight complementary DNAs (cDNAs) to the 3′-terminal region of RNAs from four groups of RNA phages were synthesized by reverse transcriptase from avian myeloblastosis virus (AMV) and were used for RNA-cDNA hybridization tests. RNAs from one serological group were annealed in extremely high frequency with a cDNA complementary to an RNA from the same group. On the other hand, when annealed with RNAs from other groups, the frequency of hybrid formation was as low as that annealed with tRNA. These results suggest that RNA sequences in the 3'-terminal untranslated region are similar in serologically same groups.
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