Abstract

The infective agent responsible for homologous serum jaundice or serum hepatitis is thought to be a virus. It is transmitted by transfusion or inoculation in man by human products, particularly by blood, plasma or serum, but it has not been successfully transmitted to other species. The disease has been produced in human volunteers by as little as 0.1 cc. of infected plasma. 1 For this reason, one donor who is a carrier of the disease can infect an entire pool of plasma. It has been recommended that the donor population of pooled plasma not exceed five and that plasma be used only as an emergency measure. As a consequence, plasma is not used as extensively as before. This hazard of pooled plasma must be overcome if it is to be stockpiled and used for civilian defense. The purpose of this report is twofold: first, to call attention to the fact

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