Homologous Recombination and Integration of Foreign DNA in Plastids of Higher Plants

Abstract

Gene targeting by homologous recombination in the nuclear genome of flowering plants is a rare event, as discussed in other chapters in this volume. In contrast, in the plastid genetic compartment, homologous recombination is the rule. Most direct evidence for homologous recombination in plastids was obtained during studies of incorporation of foreign DNA into the plastid genome. Therefore, homologous recombination in this review will be discussed in the context of plastid engineering in tobacco (Nicotiana tabacum), a flowering plant species.