Abstract
Recent work is reviewed concerning the synthesis of estrone or estradiol homologues, of interest in diagnostics, drug discovery research etc. The survey is limited to reactions where a carbon atom or a carbon chain becomes directly attached to the steroid ring system. Also conversions of non-estranoid starting materials to substituted estrone/estradiol derivatives are discussed. The organization of the review follows steroid numbering. Keywords: hydroxymethylated derivative, estrogen derivatives, Barton-McCombie deoxygenation, C-alkylation, Wolff-Kishner reduction
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