Abstract
Introduction: The aim of this systematic review is to consider the evidence base for home-based high intensity interval training (HIIT) in patients with intermittent claudication (IC). Prior knowledge of the evidence base suggests that there may be little research considering HIIT in patients with IC. If so, the evidence base across all cardiovascular diseases will be considered. Methods: Medline, EMBASE, CINAHL and Cochrane CENTRAL databases will be searched for terms including ‘peripheral arterial disease’, ‘intermittent claudication’, ‘home-based exercise’, ‘high intensity interval training’ and ‘home-based high intensity interval training’. All prospective randomised trials and non-randomised studies considering home-based HIIT in patients with IC will be included. Studies will not be excluded based on the use of a comparator arm, meaning single-arm studies as well as multi-arm trials will also be included. If appropriate, based on the extant literature, a meta-analysis of randomised controlled trials will be conducted. The outcomes of interest will include intervention components, intervention feasibility (based on uptake and completion rates), intervention tolerability (based on compliance and adherence to the intervention), maximum walking distance, pain-free walking distance, quality of life and cardiorespiratory fitness. Conclusion: This review aims to assess the evidence for home-based HIIT in patients with IC, to establish its feasibility and to inform the refinement of an existing supervised HIIT intervention to allow it to also be delivered remotely. Following this, a pilot randomised controlled trial to compare HIIT versus usual care supervised exercise programmes will be developed. For this, the interventions will be delivered either in person or remotely in real-time, depending on centre availability and patient preference.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Vascular Societies Great Britain & Ireland
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
