Abstract

BackgroundChronic diseases are rapidly increasing and are currently the major cause of death and disability worldwide. Patients with chronic diseases experience many challenges including medicine-related problems. However, there is limited information about the home management of medicines among these patients. This study therefore was to determine home medication management practices and associated factors among patients with chronic diseases seeking care in a community pharmacy in Uganda.MethodsA cross-sectional study was conducted in a community pharmacy in Kampala from June to July 2010. A total of 207 consenting chronic disease patients or caregivers of children with chronic disease were consecutively sampled. The patients were visited at home to evaluate their drug management practices and to check their medical forms for disease types and drugs prescribed. An interviewer-administered questionnaire and an observation checklist were used to collect the data.ResultsOverall home medication management was inappropriate for 70% (n = 145) of the participants (95% CI = 63.3-76.2) and was associated with perceived severity of disease (not severe OR =0.40, moderately severe OR = 0.35), duration of disease >5 years (OR = 2.15), and health worker not assessing for response to treatment (OR = 2.53). About 52% (n = 107) had inappropriate storage which was associated with inadequate information about the disease (OR = 2.39) and distance to the health facility >5 kilometres (OR = 2.82). Fifteen percent (n = 31) had no drug administration schedule and this was associated with increasing age (OR = 0.97), inadequate information about the disease (OR = 2.96), and missing last appointment for medical review (OR = 6.55). About 9% (n = 18) had actual medication duplication; 1.4% (n = 3) had expired medicines; while 18.4% (n = 38) had drug hoarding associated with increasing number of prescribers (OR = 1.34) and duration of disease (OR = 2.06). About 51% (n = 105) had multiple prescribers associated with perceiving the disease to be non severe (OR = 0.27), and having more than one chronic disease (OR = 2.37).ConclusionsPatients with chronic disease have poor home management of medicines. In order to limit the occurrence of poor outcomes of treatment or drug toxicity, health providers need to strengthen the education of patients with chronic disease on how to handle their medicines at home.

Highlights

  • Chronic diseases are rapidly increasing and are currently the major cause of death and disability worldwide

  • The burden of chronic diseases is rapidly increasing especially in developing countries where it is estimated that 79% of all deaths attributable to chronic diseases currently occur [2]

  • The community pharmacy where the study was conducted serves an average of 180 patients a day and of these about 15 patients have chronic diseases

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Summary

Introduction

Chronic diseases are rapidly increasing and are currently the major cause of death and disability worldwide. Patients with chronic diseases experience many challenges including medicine-related problems. This study was to determine home medication management practices and associated factors among patients with chronic diseases seeking care in a community pharmacy in Uganda. Chronic conditions are often accompanied by numerous challenges including medicines-related problems [3] because of the prolonged period over which patients take medication and the large number of drugs they usually take. The medicinesrelated problems include: polypharmacy, non-adherence to prescribed medicines, development of adverse events, inappropriate prescribing and dispensing, inadequate monitoring of treatment and poor home management of medicines. Most studies on medicines-related problems have looked at non-adherence, polypharmacy and inappropriate prescribing [4]. Poor home management of medicines includes poor drug storage practices, lack of medication administration schedule, use of drugs from multiple prescribers, use of discontinued medicines, expired drugs or drugs that are no longer needed and use of over-the-counter drugs which are not suitable for their condition [5]

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