Abstract
To determine which of two simplified blood glucose monitoring schemes promotes better metabolic control in type 1 diabetic patients during 12 months of participation in educational groups. A crossover clinical trial involving 21 patients divided into two groups was conducted. They were submitted to a two monitoring schemes: 2 alternate daily preprandial measurements and 2 alternate daily pre-and postprandial measurements. The effectiveness of the schemes was evaluated based on HbA1c. Variations in mean HbA1c were analyzed by Friedman test. The groups were homogenous in terms of sociodemographic and clinical variables (p>0.05). Mean HbA1c levels ranged from 8.48 (+/-1.00) to 7.37 (+/-0.99) over time in Group A and from 9.89 (+/-0.86) to 8.34 (+/-1.06) in Group B. The analysis of the HbA1c showed a significant reduction in the first and last 6 months and over the 12 months of the study in two groups (p<0.05). The preprandial scheme demonstrated the largest number and highest percentage of significant drops in HbA1c. The two monitoring improved the metabolic control and the preprandial scheme was more effective.
Highlights
One of the most significant studies to test the proposal that complications of Type 1 Diabetes Mellitus (DM1) are related to a chronic increase in blood glucose was the Diabetes Control and Complications Trial (DCCT)(1)
As demonstrated in other studies, these results confirm that, when a monitoring program is encouraged[3,4,5] or when glycemic values are used to understand the interaction between insulin therapy, diet, physical activity and complications and to guide treatment, blood glucose monitoring effectively improves metabolic control and treatment compliance increases both among young patients and among those above the age of 60(5-7)
In a study evaluating the effect of an insulin therapy regimen on metabolic control in 229 children, it was demonstrated that an increase in the frequency of blood glucose monitoring (1 to 6 times per day) was correlated with lower HbA1c (r=-0.15, p=0.006), with each additional daily monitoring resulting in a 0.4% decrease in HbA1c concentration, and that the number of insulin types and applications was correlated with increased HbA1c (r=0.2, p=0.02), with each additional insulin dose resulting in a 0.46% increase in HbA1c concentration[10]
Summary
To determine which of two simplified blood glucose monitoring schemes promotes better metabolic control in type diabetic patients during 12 months of participation in educational groups. Methods: A crossover clinical trial involving 21 patients divided into two groups was conducted They were submitted to a two monitoring schemes: alternate daily preprandial measurements and 2 alternate daily pre-and postprandial measurements. Objetivo: Identificar cual de los dos esquemas de monitorización propuestos posibilita realizar un mejor control metabólico, en diabéticos del tipo, durante los 12 meses de participación en grupos educativos. Resultados: Durante todo el estudio la variación de los promedios de HbA1c, para el grupo A, fue de 8,48(±1,00) la 7,37(±0,99) y de 9,89(±0,86) la 8,34(±1,06) para el grupo B. MONITORIZAÇÃO DOMICILIAR DA GLICEMIA EM PACIENTES COM DIABETES MELLITUS DO TIPO 1. Objetivo: Identificar qual de dois esquemas simplificados de monitorização da glicemia viabiliza melhor controle metabólico, em pacientes com diabetes mellitus tipo 1, ao longo de 12 meses de participação em grupos educativos.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
