Abstract
Canton of Zurich ethics committee (EK-24/2009, PB_2016-00545), ClinicalTrials.gov: NCT02149186. Registered 24 April 2014.
Highlights
An injured spinal cord leads to diminished functional recovery
Augmented exercise therapy has been shown to have favorable effects on rehabilitation outcomes in subjects with incomplete spinal cord injury and stroke [7, 8], and longer training duration is referred to higher walking function [9, 10]
The secondary outcome measures showed with respect to walking speed/distance and mobility no significant effects: 10 m walking test (10MWT) (P = 0.169), 6 min walking test (6minWT) (P = 0.037); Spinal Cord Independence Measure (SCIM) III mobility (P = 0.018), and Walking Index for Spinal Cord Injury (WISCI) II (P = 0.180)
Summary
An injured spinal cord leads to diminished functional recovery. From pre-clinical studies it is known that active rehabilitative training is crucial to promote and enhance functional recovery [4]. Augmented exercise therapy has been shown to have favorable effects on rehabilitation outcomes in subjects with incomplete spinal cord injury (iSCI) and stroke [7, 8], and longer training duration is referred to higher walking function (dose–response context) [9, 10]. Beside the amount of training, active participation is a key element for functional improvements [11]. To increase active participation of subjects during therapy sessions virtual reality (VR) scenarios may have a beneficial effect on motivation [12, 13] and increase rehabilitation success [14, 15]. It is possible to provide biofeedback and multimodal sensory stimuli which can be interactively used [16]
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