Abstract

The public health concern is very important for the growing burden of chronic metabolic disease like Diabetes mellitus. It is foreseeable that by 2045 India would reach rank first in Type-2 Diabetes Mellitus which contributes to 90% of diabetes. Therefore, more care or attention should be given to this disease. There are so many medications available in the market including herbal drugs. But due to more side effects of oral hypoglycemic agents, attention grabs more towards the alternative of synthetic drugs or using Nano-carriers to avoid side effects. Presently, many novel drug delivery systems for oral hypoglycemic agents are available in the market. But herbal drugs grab more attention due to lesser side effects, efficacy and cost-effective. However, there is very less work is reported on nanotechnology like liposomes, nanoparticles/microparticles, gold nanoparticles, noisome, and nano-capsules/microcapsules of herbal drugs, which is currently emerging therapy for diabetes. Nanotechnology or a novel drug delivery system for herbal medicine can be used to overcome the challenges like poor bioavailability, efficacy and stability problems. The current review emphasizes current epidemiology, its types, complications and management of different treatment strategies for diabetes mellitus. Furthermore, the problems related to herbal medicine with immense hope for herbal medicine using nanotechnology are discussed.

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