Abstract
Background: Idiopathic cholestasis is a rare presentation of Hodgkin's lymphoma. We report a case with this diagnosis and review the literature. Case Description: A 26-year-old male presented with Hodgkin's lymphoma, stage IIIs with elevated serum bilirubin level up to 30 mg/dL. Idiopathic cholestasis was diagnosed after exclusion of other possibilities of jaundice. Radiotherapy was performed first, and the cholestasis gradually improved, which allowed subsequent standard systemic chemotherapy. After completion of chemotherapy, the disease status was partial remission, and the patient's serum bilirubin level returned to normal. He was alive and free of recurrence 16 months after diagnosis. Conclusions: Idiopathic cholestasis is a diagnosis of exclusion. Prompt remission induction provides the chance to liver function recovery and long-term survival.
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