Abstract
In this issue of Blood , Cozen and colleagues report on cytokine levels and the presence of a genetic polymorphism in the twins of patients with young-adult Hodgkin lymphoma. The analysis focuses on interleukin-12 in monozygotic twins, dizygotic twins, and control donors. The results suggest an interesting hypothesis that builds on the “polio” and “hygiene” hypotheses that have previously been offered to explain the epidemiology of young-adult Hodgkin lymphoma.
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