Abstract
The hobnail variant of papillary thyroid carcinoma (HVPTC) is a newly described aggressive variant relative to that of the classical PTC. There have been genetic markers like the BRAF V600E mutation associated with more aggressiveness and a higher rate of recurrence and mortality. Here we discuss a case of thyroid swelling which clinically resembled a thyroglossal cyst due to movement of the swelling with tongue protrusion. Imaging indicated a multilobulated cystic swelling arising from the thyroid gland. FNAC was suggestive of colloid goitre. Total thyroidectomy was done and histopathology revealed HVPTC.HVPTC is an aggresive variant and if diagnosed preoperatively may warrant more extensive surgery. One must also have a high index of suspicion for thyroid swellings that are large with variable clinical presentations (including mutiple septations) as they may appear benign on FNAC but may prove to be malignant on histopathology.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
