Abstract
The frequency of HLA markers associated with rapid progression from HIV infection to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not exhibiting cytomegalovirus retinitis (CMV-R). A total of 124 AIDS patients (44 with and 80 without CMV-R) were studied. HLA markers associated with rapid progression to AIDS were significantly increased in the CMV-R group compared with those without retinitis. The presence of these HLA markers may simultaneously predispose to AIDS and CMV-R.
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