Abstract
10 affected children /AGS/ and 3 healthy sibs from 11 families were typed for HLA-A and B antigens by the standard NIH lympho-cytotoxicity test. In one family two affected sibs shared both HLA haplotypes. Neither of the healthy sibs had HLA-haplotypes identical to the affected patients. As regards the individual HLA-types, B5/chi2=1,661/B7/chi2=0,062/, B40/ chi2=1,272/ seem to emerge as more frequent than the average, but with the population frequency based on 222 healthy blood donors' HLA-A-B antigen frequencies there was no significant difference.
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