HLA‐G 14bp del/ins genetic variation: association with susceptibility to human immunodeficiency virus‐1 vertical transmission but not with human immunodeficiency virus‐1 infection through horizontal transmission

Abstract

We discuss herein the possible involvement of human leukocyte antigen (HLA)‐G 14bp del/ins polymorphism in human immunodeficiency virus (HIV) infection. Based on previous results and reports, we suggest that HLA‐G should be considered, in the context of HIV‐1 infection, as a candidate molecule for the susceptibility to HIV‐1 mother‐to‐child transmission, rather than for HIV‐1 horizontal transmission for which no consensus findings and hypothesis have been reported so far.