Abstract

We note with great interest the publication by Stern et al, which evaluated the hypothesis that human leukocyte antigen (HLA) DR15 would reduce relapse rate and improve survival in patients receiving allogeneic stem cell transplantation [1]. We had previously examined this hypothesis in our single center study of 119 consecutive related and 48 consecutive unrelated myeloablative allogeneic blood and marrow transplant (BMT) for myeloid malignancies to investigate the influence of HLA DR15 on overall survival (OS), progression-free survival (PFS), and incidence of grades II to IV acute graft-vs-host-disease (GVHD) [2].

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