Abstract
A predictive biomarker for sublingual immunotherapy (SLIT) efficacy is not available for patients with allergic rhinitis (AR). Amino acid changes in the allergen-binding pocket of HLA-DPB1 were associated with the development of Japanese cedar (JC) pollinosis and sensitization to JC pollen. The aim of this study was to investigate whether the HLA-DPB1 gene is associated with SLIT responsiveness in patients with JC pollinosis.
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